TRANSFORMATION STUDIES IN BACTERIAL SYSTEMS USING GOLD NANOPARTICLES
Published: 2008
Author(s) Name: Prajakta S. Karekar, Radhika S. Ganu, Akhilesh Rai, Kalpana S. Joshi, Murali Sastry
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Abstract
INTRODUCTION -
Nanotechnology has wide applications in biology
and medicine. Nanoparticles can be made as carriers
for delivering macro molecules such as DNA and
proteins. Most DNA delivery systems operate at one
of three general levels: DNA condensation and
complexation, endocytosis, and nuclear targeting/
entry1. Gene delivery systems are broadly classified
into two broad categories-Viral vectors and non-viral
vectors. The synthetic properties of non-viral vectors
gives them the advantage over viral vectors in the area
of transgene insert capacity, cost, time, general
safety, and delivery to cell lines grown in vitro
Keywords: Bacterial system, Gold Nanoparticles
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