The emergence of the digital economy is redefining how businesses function, engage with stakeholders and what is expected of them as responsible entities. The expanding scope and reach of digital technologies into economic and social systems worldwide is transforming Corporate Social Responsibility (CSR) from a voluntary business activity to a core sustainability-led business imperative. In this article, authors explore how organisations are embedding sustainability and CSR initiatives in the digital economy and provide comparative insights through examples from large and small businesses. Secondary research and publicly available corporate information was used to present two case examples of large digital intensive companies (Microsoft and Amazon) and two smaller technology enabled companies (Birlasoft and Indian digital start-up eSamudaay) that have used digital technology to further social causes such as environmental sustainability, social inclusion, bridging digital divide and community development. A comparison between the larger corporations and smaller organisations illustrates how CSR and the mandate for responsible business are meeting digital technologies at different levels. Organisations irrespective of size and stature are adopting sustainability-driven CSR initiatives as integral to their business in the digital economy. This article provides a snapshot into the evolving discourse on responsible digitalisation by offering examples of how value can be created for society through responsible business in the digital age.