Studies on managerial topics in India, especially on human resource management specified several factors having direct impacts upon individual and organizational effectiveness. Organizational culture and transformational leadership were found to have important bearing upon human resource development and the performance of individual employees. This study explores the effect of organizational culture and transformational leadership on individual’s intention to quit his/ her present organization. The study focuses upon the role played by organizational communication in mediating the relationship between the predictors and the criteria variables. Data for this research were collected from 357 managers/ executives of different organizations in India and were subject to multivariate data analysis procedures. Keywords : Organizational culture and transformational leadership, organizational communication