This article discusses the relationship between talent management and organizational culture. Talent management is associated with various human resource practices and is gaining importance in organizations in order to achieve competitive advantage. Organizational culture is developed by leaders in the organization which encompasses core values and beliefs. Different types of organizational culture that exist in organization is discussed, such as bureaucratic, entrepreneurial clan and marketing along with strong and weak cultures. Organizational culture is associated with various functions and one of them is effective talent management. Organizational culture is also associated with business strategy to gain competitive advantage. Latest trends in business scenario with respect to organizational culture have also been discussed.