The present study aims at investigating effect of structural empowerment on organizational citizenship behavior of auxiliary nurse and midwives. The study was conducted using standardized questionnaires. Responses were gathered from 178 auxiliary nurse and midwives working in primary healthcare centres in Chirang and Kokrajhar districts of Assam. The relationship between structural empowerment and organizational citizenship behavior was assessed using structural equation modeling. The proposed research model was able to explain11. 9% of variation in organizational citizenship behavior. The result is important to understand the role of structural empowerment in predicting organizational citizenship behavior of auxiliary nurse and midwives. This is very essential as higher degree of organizational citizenship behavior leads to improved attraction and retention of auxiliary nurse and midwives, which may ultimately serve to improve patient outcomes.